Combating Antibiotic Resistance From the Ground Up
Elie Dolgin • October 18, 2016
Whenever anyone from Gerry Wright’s laboratory goes on vacation, they come back with a small plastic bag of dirt. Usually these muddy mementos yield nothing of interest. But one graduate student’s soil souvenir from a hiking trip in Eastern Canada produced a compound that could hold the key to combating one of the world’s most insidious groups of superbugs.
In response to cellular stress, proteins become ensnared in chemical traffic jams, creating a kind of widespread sluggishness scientists call “proteolethargy.”
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