How cells' 'lava lamp' effect could make cancer drugs more powerful
Elie Dolgin • June 18, 2020
Discovery that synthetic compounds form concentrated droplets inside cells could shake up drug development — including the hunt for coronavirus treatments.
There’s a long-standing assumption in the pharmaceutical industry that when drug molecules enter a cell, they spread through it evenly — but, says biologist Rick Young, “that could not be further from the truth”.
Continue reading at Nature.
How a tissue-swelling method brought super-resolution imaging to the masses.
In response to cellular stress, proteins become ensnared in chemical traffic jams, creating a kind of widespread sluggishness scientists call “proteolethargy.”